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Ophthalmic squeeze dispenser (OSD) from Aptar Pharma with components made of medical grade THERMOLAST M from Kraiburg for direct contact with medications.
Ophthalmic squeeze dispenser (OSD) from Aptar Pharma with components made of medical grade THERMOLAST M from Kraiburg for direct contact with medications.

Aptar Pharma launched its ophthalmic squeeze dispenser (OSD), with several functional components manufactured using a newly developed, medical grade thermoplastic elastomer (TPE) from Kraiburg TPE.

Due to its microbiological safety as well as easy and precise dosing capabilities, the ophthalmic squeeze dispenser from Aptar Pharma is in widespread use as dispenser for eye drops that contain no preservatives.

To further optimize the product, the manufacturer sought a thermoplastic processable material that allows direct contact with medications. Kraiburg TPE's THERMOLAST M material was chosen for the production of a new component.

"In close cooperation with Kraiburg TPE we were able to further improve the exemplary safety and integrity of the ophthalmic squeeze dispenser from Aptar Pharma, without compromising its intuitive and convenient use," said Stefan Ritsche, President Global Market Development at Aptar Pharma.

THERMOLAST M compounds are tested in accordance with relevant standards such as USP Class VI, ISO 10993-4 (haemolysis), ISO 10993-5 (cytotoxicity), ISO 10993-10 (intracutaneous irritations) and ISO 10993-11 (acute system toxicity). In addition, a drug master file (DMF) for the materials is on file with the US Food & Drug Administration (FDA).

The ophthalmic squeeze dispenser from Aptar Pharma is the only reusable dosing system thus far approved by the FDA for liquid medications that do not contain preservatives. The design contains no metal parts whatsoever in the drug flux and is therefore also suitable for very sensitive formulations. The purely mechanical functioning principle of the seal membrane and spring unit eliminates the possibility of microbiological contamination of the liquid.

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