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Home > News > Medical

New vitamin E antioxidant PE approved for knee replacement use

Source：Adsale Plastics Network Date ：2023-08-29 Editor ：RC
Copyright： Original work. Please do not reprint.

Exactech, a developer and producer of innovative implants for joint replacement surgery, announced 510(k) clearance from the US Food and Drug Administration for its new Activit-E polyethylene (PE) for the Truliant knee replacement system.

 

Activit-E is a crosslinked PE with vitamin E antioxidant. The PE is peroxide crosslinked and stabilized with vitamin E. The material is designed to maintain active oxidative resistance and long-term, high-performance, including strength and stabilization.


activit E_480.jpg

Exactech’s new Activit-E Knee Replacement Polyethylene.

 

This new generation PE is the latest innovation by Orhun Muratoglu, Ph.D., Director of the Harris Orthopedic Laboratory at Massachusetts General Hospital in Boston. Muratoglu invented the first crosslinked polyethylene, and the first of multiple generations of vitamin E antioxidant PE for leading orthopedic companies.

 

Through replacing gamma radiation crosslink with peroxide crosslink, the chemically crosslinked PE brings an optimized balance of material strength, toughness and flexibility, which is ultimately useful in total knee arthroplasty.

 

Eliminating the need for gamma irradiation technology used in previous generation PE also addresses the looming shortage problem of gamma radiation for crosslink.

 

The first products for Activit-E will launch in the beginning of Q3 2023 for selected US customers while global expansion will begin in 2024.


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Medical
Polyethylene (PE)
Orthopedic implant
 USTAB CHEM INTERNATIONAL COMPANY LIMITED      
 Ningxia Baofeng Energy Group Co., Ltd.      
 CHISAGE ENERGY AND CHEMICAL CO., LTD.      
 OQ Marketing (Shanghai) Co., Ltd.      
 WUHAN CHANGXIN PLASTIC MACHINERY CO.,LTD.      
 Rongsheng Petrochemical Co., Ltd.      
 DSP CHEMICAL CO.,LTD      
 Inner Mongolia Dadi Yuntian Chemical Co..Ltd      
 HUAJIN ARAMCO PETROCHEMICAL COMPANY LIMITED      
 MOTAN TAICANG CO., LTD.      
 SHANGHAI HUIDE SCIENCE AND TECHNOLOGY CO., LTD.      
 Lanzhou Auxiliary Agent Plant Co., Ltd      
 Taizhou Huangyan Zhengwei Mould Co.,Ltd      
 SUZHOU UNIKING NEW MATERIAL CO., LTD      
 Zhejiang Future Petrochemical Co.,ltd      
 Beijing Chemical Industry Group CO.,LTD      
 CHUZHOU SEP MATERIAL CO,LTD.      
 Guangdong MEIJOY Products Co., Ltd      
 HENAN SHUOPENG NEW MATERIALS TECHNOLOGY CO., LTD      

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Source：Adsale Plastics Network Date ：2023-08-29 Editor ：RC
Copyright： Original work. Please do not reprint.

Exactech, a developer and producer of innovative implants for joint replacement surgery, announced 510(k) clearance from the US Food and Drug Administration for its new Activit-E polyethylene (PE) for the Truliant knee replacement system.

 

Activit-E is a crosslinked PE with vitamin E antioxidant. The PE is peroxide crosslinked and stabilized with vitamin E. The material is designed to maintain active oxidative resistance and long-term, high-performance, including strength and stabilization.


activit E_480.jpg

Exactech’s new Activit-E Knee Replacement Polyethylene.

 

This new generation PE is the latest innovation by Orhun Muratoglu, Ph.D., Director of the Harris Orthopedic Laboratory at Massachusetts General Hospital in Boston. Muratoglu invented the first crosslinked polyethylene, and the first of multiple generations of vitamin E antioxidant PE for leading orthopedic companies.

 

Through replacing gamma radiation crosslink with peroxide crosslink, the chemically crosslinked PE brings an optimized balance of material strength, toughness and flexibility, which is ultimately useful in total knee arthroplasty.

 

Eliminating the need for gamma irradiation technology used in previous generation PE also addresses the looming shortage problem of gamma radiation for crosslink.

 

The first products for Activit-E will launch in the beginning of Q3 2023 for selected US customers while global expansion will begin in 2024.


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New vitamin E antioxidant PE approved for knee replacement use

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